Asian patients with gastric carcinoma in the United States exhibit unique clinical features and superior overall and cancer specific survival rates

5 Background: Gastric cancer is one of the leading causes of cancer related deaths worldwide with the incidence declining in the United States. However the prognosis remains poor with variable survivals being reported among different races. We analyzed the effect of race on patterns of disease presentation and survival rates using the Surveillance, Epidemiology, and End Results (SEER) database. Methods: A total of 9,851 patients were diagnosed with gastric cancer from year 2004 to 2007 were identified from SEER database. Age, race, TNM staging, grade, treatment modalities utilized and cancer specific survival was collected. Results: Out of 9,851 patients, 64.63% were white, 12.17% were black, and 13.04% were Asian-Pacific islanders. Median age was 73 years for whites, 70 years in blacks, and 71 years in Asians. Sex distribution amongst races was more or less similar with 58.83% of whites, 59.47% of blacks, and 54.24% of Asians being men. 23.62% of whites had T1 lesions, 28.10% had T2, 19.58% were T3 and 28.70% had T4 lesions. 26.76% of blacks presented with T1 lesions, 26.63% with T2, 16.08% with T3 and 30.53% with T4. 18.69% of Asians had T1 lesions, 26.84% with T2, 23.44% had T3 and 31.03% had T4 lesions. 37.80% of whites, 36.70% of blacks, and 44.44% of Asians had lymph node involvement. Tumor grade was similar among all races. Surgery was performed in 31.49% of whites, 33.13% of blacks, and 40.48% of Asians. 14.68% of whites, 14.10% of blacks, and 19.43 % of all Asians underwent radiation therapy. Median overall survival in localized disease was 44 months, 43 months and 98 months (p < 0.0001) while in regional disease it was 16 months, 15 months and 23 months in whites, blacks and Asians respectively (p < 0.0001). Median survival in distant disease was 4 months in both whites and blacks; it was 5 months in Asians (p < 0.0001). Conclusions: Cancer-specific survival in gastric carcinoma is significantly better in localized, regional and metastatic disease in Asians when compared to whites and blacks independent of T stage, grade, nodal involvement and treatment modalities utilized. The reason for this observation is unclear, exposure and genetic factors are potential causes and this needs to be investigated. No significant financial relationships to disclose.

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Differential Trends in the Intestinal and Diffuse Types of Gastric Carcinoma in the United States, 1973-2000: Increase in the Signet Ring Cell Type

Yearbook of Pathology and Laboratory Medicine ◽

10.1016/s1077-9108(08)70016-1 ◽

2006 ◽

Vol 2006 ◽

pp. 17-18

Author(s):

P.A. Bejarano

Keyword(s):

United States ◽

Gastric Carcinoma ◽

The United States ◽

Signet Ring Cell ◽

Cell Type ◽

Signet Ring ◽

Ring Cell

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Breast cancer survival rates among Chinese women born in East Asia and the United States

Annals of Epidemiology ◽

10.1016/j.annepidem.2005.06.013 ◽

2005 ◽

Vol 15 (8) ◽

pp. 634-634

Author(s):

S CHUANG ◽

W CHEN ◽

M HASHIBE ◽

G LI ◽

P GANZ ◽

...

Keyword(s):

Breast Cancer ◽

United States ◽

East Asia ◽

Cancer Survival ◽

Chinese Women ◽

Survival Rates ◽

The United States ◽

Breast Cancer Survival

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EPID-10. GLIOMA INCIDENCE AND SURVIVAL BY INCOME LEVEL IN THE UNITED STATES GENERAL POPULATION AGES AND ABOVE FROM 2000-2018

Neuro-Oncology ◽

10.1093/neuonc/noab196.343 ◽

2021 ◽

Vol 23 (Supplement_6) ◽

pp. vi87-vi88

Author(s):

Jennifer Murillo ◽

Elizabeth Anyanda ◽

Jason Huang

Keyword(s):

United States ◽

General Population ◽

Survival Data ◽

Survival Rates ◽

The United States ◽

Income Level ◽

Population Based ◽

Research Database ◽

Income Levels ◽

Average Survival

Abstract Gliomas are the most common primary malignant brain tumor in the United States with previous studies showing the incidence varied by age, sex, and race or ethnicity. Survival after diagnosis has also been shown to vary by these factors. Also, socioeconomic status and its association with various cancers have also been studied at length over time. PURPOSE: The purpose of our research was to quantify the differences in incidence and survival rates of gliomas in 15 years and older by income level. METHODS: This population-based study obtained incidence and survival data from the Incidence-SEER Research Database the general population. Average age incidence were generated by glioma groups and grouped by income levels. Survival rates were generated by overall glioma diagnosis grouped by observed survival at 12, 24, 36, 48 and 60 months and by again by income levels. The analysis included 94,207 patients with glioma diagnosed in those aged 15 years or older. RESULTS: Overall, 94, 207 patients diagnosed with glioma were analyzed. Of these, 1,089 (1.16%) fell into the < $35k group, 1,684 (1.79%) in the $35k-$40k group, 3,473 (3.69%) in the $40k-$45k group, 5,647 (5.99%) in the $45k-$50k group, 7,138 (7.58%) in the $50k-$55k group, 6,468 (6.87%) in the $55k-$60k group, 15,348 (16.29%) in the $60k-$65k group, 13,216 (14.03%) in the $65k-$70k group, 9,035 (9.59%) in the $70k-$75k group, and 31,109 (33.02%) fell in > $75k group. The data was also broken further down into survivability showing average survival. CONCLUSION: Incidence of glioma and 12, 24, 36, 48 and 60 month survival rates after diagnosis vary significantly by income level with higher income level greater than $75,000+ having higher incidence and higher survival rates compared with lower income levels. Further research is needed to help determine risk factors and barriers to care to help reveal health disparities.

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Clinical Features of Moyamoya Disease in the United States

Stroke ◽

10.1161/01.str.29.7.1347 ◽

1998 ◽

Vol 29 (7) ◽

pp. 1347-1351 ◽

Cited By ~ 174

Author(s):

David Chiu ◽

Peter Shedden ◽

Patti Bratina ◽

James C. Grotta

Keyword(s):

United States ◽

Clinical Features ◽

Moyamoya Disease ◽

The United States

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Long-term trends and drought: spatiotemporal variation in juvenile sex ratios of North American ducks

10.22541/au.163585615.56294256/v1 ◽

2021 ◽

Author(s):

Sage Ellis ◽

Madeleine Lohman ◽

James Sedinger ◽

Perry Williams ◽

Thomas Riecke

Keyword(s):

United States ◽

North American ◽

Sex Ratios ◽

Survival Rates ◽

The United States ◽

Avian Communities ◽

Eastern United States ◽

Bird Populations ◽

Long Term Trends

Sex ratios affect population dynamics and individual fitness, and changing sex ratios can be indicative of shifts in sex-specific survival at different life stages. While climate- and landscape-change alter sex ratios of wild bird populations, long-term, landscape scale assessments of sex ratios are rare. Further, little work has been done to understand changes in sex ratios in avian communities. In this manuscript, we analyse long-term (1961-2015) data on five species of ducks across five broad climatic regions of the United States to estimate the effects of drought and long-term trends on the proportion of juvenile females captured at banding. As waterfowl have a 1:1 sex ratio at hatch, we interpret changes in sex ratios of captured juveniles as changes in sex-specific survival rates during early life. Seven of twelve species-region pairs exhibited evidence for long-term trends in the proportion of juvenile females at banding. The proportion of juvenile females at banding increased for duck populations in the western United States and typically declined for duck populations in the eastern United States. We only observed evidence for an effect of drought in two of the twelve species-region pairs, where the proportion of females declined during drought. As changes to North American landscapes and climate continue and intensify, we expect continued changes in sex-specific juvenile survival rates. More broadly, we encourage further research examining the mechanisms underlying long-term trends in juvenile sex ratios in avian communities.

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Cancer Survival Is (Mostly) Improving

Pained ◽

10.1093/oso/9780197510384.003.0070 ◽

2020 ◽

pp. 245-246

Author(s):

Michael D. Stein ◽

Sandro Galea

Keyword(s):

Prostate Cancer ◽

United States ◽

Pancreatic Cancer ◽

Survival Rate ◽

Cancer Diagnosis ◽

Cancer Survival ◽

Prostate Cancer Screening ◽

Survival Rates ◽

The United States ◽

Cervical Cancers

This chapter discusses how the 5-year survival rates for the most common cancers in the United States improved by nearly 20% since the 1970s. While promising overall, low survival rates persist for pancreatic, liver, lung, esophageal, brain, and many other cancers. Meanwhile, 5-year survival for uterine and cervical cancers worsened. Pancreatic cancer has the lowest 5-year survival rate at 8.2%. In contrast, prostate cancer had the greatest 5-year survival increase from 67.8% to 98.6%, most likely reflecting a substantial uptick in prostate cancer screening and early detection. Five-year survival with leukemia also improved significantly, from 34.2% to 60.6%, likely resulting from improved treatments. As such, in both detection and treatment, the United States is making progress. For the millions of Americans who face a cancer diagnosis, this is cause for hope.

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